Dr Connor Sharp
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Lecturer in Biomedical Sciences
Areas of interest
Connor's research focusses on the mechanisms bacteria use to compete with each other, and how we can use these mechanisms to prevent or treat infection.
His current projects include:
• The interplay between bacterial warfare and nutrient competition in the microbiome
• The evolution of resistance to protein antimicrobials
• Optimising protein antimicrobial treatment using experimental evolution
• Discovery of novel candidate antibiotics using bioinformatics
Research Centres and groups
National Collaborators
• Prof Kevin Foster – ¶¶Òõ of Oxford
International collaborators
• Dr Olivier Cunrath – ¶¶Òõ of Strasbourg
• Dr Sean Booth – ¶¶Òõ of Manitoba
Teaching
- Part 2: Infectious Diseases, The Bacterial Cell
- Part 3: Pathogens
Background
2009-2013: BSc Molecular Biology ¶¶Òõ of Exeter
2013-2017: DPhil Biochemistry, ¶¶Òõ of Oxford
2017-2023: Postdoctoral research associate, ¶¶Òõ of Oxford
2024-present: Lecturer in Biomedical Science, ¶¶Òõ of Reading
Selected publications
Sharp C, Foster KR (2022) Host control and the evolution of cooperation in host microbiomes.
Atanaskovic I, Sharp C, Press C, Kaminska R, Kleanthous C. (2022) Bacterial Competition Systems Share a Domain Required for Inner Membrane Transport of the Bacteriocin Pyocin G from Pseudomonas aeruginosa mBio.
Sharp C, Boinett C, Cain A, Housden NG, Kumar S, Turner K, Parkhill J, Kleanthous C. (2019) O-Antigen-Dependent Colicin Insensitivity of Uropathogenic Escherichia coli.